Nakamura T, Tatara N, Morisaki K, Kawakita K, Nagao S
Department of Neurosurgery, JA-Kagawa Takinomiya General Hospital, Ayautagun, Kagawa, Japan.
Acta Neurol Scand. 2002 Nov;106(5):314-8. doi: 10.1034/j.1600-0404.2002.01300.x.
The significance of cerebral oxygen metabolism monitoring under hypothermia for severe subarachnoid hemorrhage (SAH) was studied.
Cerebral oxygen metabolism monitoring (jugular venous oxygen saturation: SjO2, arterio-jugular venous difference of oxygen: AJDO2, and oxygen extraction fraction:OEF) during hypothermia (32-34 degrees C) was evaluated in eight patients with SAH (severe vasoapasm group: five patients, and severe brain damage group: three patients).
In favorable cases in both groups, each parameter tended to normalize during hypothermia therapy. When changes in SjO2 were normal, however, the value of AJDO2 was low in unfavorable cases in the severe vasospasm group. In unfavorable cases in the severe brain damage group, high level of SjO2 and low level of OEF and AJDO2 were shown even if hypothermia therapy was performed.
The measurement of SjO2 and AJDO2 is useful for estimation of cerebral oxygen metabolism in patients with severe conscious disturbance after SAH under hypothermia therapy.
研究低温状态下脑氧代谢监测对重症蛛网膜下腔出血（SAH）的意义。
对8例SAH患者（重度血管痉挛组：5例；重度脑损伤组：3例）在低温（32 - 34摄氏度）期间进行脑氧代谢监测（颈静脉血氧饱和度：SjO2、动 - 颈静脉氧差：AJDO2以及氧摄取分数：OEF）。
两组病情好转的病例中，低温治疗期间各参数均趋于正常。然而，在重度血管痉挛组病情恶化的病例中，当SjO2变化正常时，AJDO2值较低。在重度脑损伤组病情恶化的病例中，即使进行了低温治疗，仍显示出SjO2水平升高、OEF和AJDO2水平降低。
SjO2和AJDO2的测量对于评估低温治疗下SAH后严重意识障碍患者的脑氧代谢是有用的。
