Short K A, Groves R W, Novelli M R
Departments of Dermatology and Histopathology, Middlesex Hospital, Mortimer Street, London, UK.
Clin Exp Dermatol. 2002 Sep;27(6):471-3. doi: 10.1046/j.1365-2230.2002.01066.x.
We describe a patient with chronic plaque psoriasis who developed haemorrhage into pre-existing lesions during an episode of disseminated intravascular coagulation secondary to sepsis. Disseminated intravascular coagulation is a complex disorder characterized by widespread intravascular deposition of fibrin with consumption of coagulation factors and platelets and occurs as a consequence of many disorders that release procoagulant material into the circulation or cause widespread endothelial damage or platelet aggregation. As both disseminated intravascular coagulation and psoriasis occur relatively frequently in the general population we were surprised to find no previous reports of this phenomenon in the literature.
我们描述了一名慢性斑块状银屑病患者,在因败血症继发的弥散性血管内凝血发作期间,原有皮损处出现出血。弥散性血管内凝血是一种复杂的病症,其特征是纤维蛋白在血管内广泛沉积,同时消耗凝血因子和血小板,它是由许多向循环系统释放促凝物质或导致广泛内皮损伤或血小板聚集的病症引起的。由于弥散性血管内凝血和银屑病在普通人群中都相对常见,我们很惊讶在文献中未发现此前关于这种现象的报道。