Marsh M E, Ridall A L, Azadi P, Duke P J
Department of Basic Sciences, The University of Texas Dental Branch, 6516 M. D. Anderson Blvd., Houston, TX 77030, USA.
J Struct Biol. 2002 Jul;139(1):39-45. doi: 10.1016/s1047-8477(02)00503-8.
The coccolithophores are valuable models for the design and synthesis of composite materials, because the cellular machinery controlling the nucleation, growth, and patterning of their calcitic scales (coccoliths) can be examined genetically. The coccoliths are formed within the Golgi complex and are the major CaCO(3) component in limestone sediments-particularly those of the Cretaceous period. In this study, we describe mutants lacking a sulfated galacturonomannan and show that this polysaccharide in conjunction with the Golgi-derived membrane is directly linked to the growth and shaping of coccolith calcite but not to the initial orientated nucleation of the mineral phase.
颗石藻是复合材料设计与合成的重要模型，因为控制其钙质鳞片（颗石）成核、生长和图案形成的细胞机制可以通过遗传学方法进行研究。颗石在高尔基体复合物中形成，是石灰岩沉积物中主要的碳酸钙成分，尤其是白垩纪时期的沉积物。在本研究中，我们描述了缺乏硫酸化半乳糖醛酸甘露聚糖的突变体，并表明这种多糖与高尔基体衍生的膜一起直接与颗石方解石的生长和形状有关，但与矿相的初始定向成核无关。
