Ingersoll I, Lell W, Allarde R, Corssen G
Anesth Analg. 1975 Sep-Oct;54(5):660-8. doi: 10.1213/00000539-197509000-00024.
A series of 110 children, ranging in age from 2 days to 4 years and in weight from 2.4 to 12.9 kg, underwent total surgical correction of complicated heart defects with the aid of profound hypothermia and total circulatory arrest. Combined surface and core cooling, in conjunction with light general anesthesia, proved to be a safe and effective method to provide optimal working conditions for the surgeon. The technic of cooling and rewarmining, as well as hemodynamic and metabolic parameters monitored, are important, and factors such as type of heart defect, age, weight should be considered in relation to postoperative morbidity and mortality.
110名年龄从2天至4岁、体重从2.4公斤至12.9公斤的儿童，在深度低温和完全循环停止的辅助下接受了复杂心脏缺陷的完全手术矫正。体表和核心联合降温，结合浅全身麻醉，被证明是为外科医生提供最佳工作条件的一种安全有效的方法。降温与复温技术，以及所监测的血流动力学和代谢参数很重要，并且应结合心脏缺陷类型、年龄、体重等因素来考虑术后发病率和死亡率。
