Wubbels R J, van Marle J, Sondag H N P M, de Jong H A A
Vestibular Department, ENT, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Brain Res Bull. 2002 Sep 30;58(6):575-80. doi: 10.1016/s0361-9230(02)00828-6.
Rats were exposed to a hypergravity (HG) level of 2.5 x g from conception until the age of 14 weeks. The vestibular epithelia of four of these animals and four control animals were immunohistochemically labeled for actin and tubulin. The apical cross-sectional area of epithelial cells of HG exposed rats appeared to be larger in all end organs. Area increase was 7.0% in the utricle (p<0.005) and 8.2% in the crista (p<<0.001). Hair cells and supporting cells appeared to be intact. The cellular arrangement and the proportion of different cell types within the epithelia was normal.
从受孕到14周龄，将大鼠暴露于2.5倍重力的超重力（HG）环境中。对其中4只动物和4只对照动物的前庭上皮进行肌动蛋白和微管蛋白的免疫组织化学标记。在所有终器中，暴露于HG的大鼠上皮细胞的顶端横截面积似乎更大。椭圆囊的面积增加了7.0%（p<0.005），嵴的面积增加了8.2%（p<<0.001）。毛细胞和支持细胞似乎完好无损。上皮内细胞排列和不同细胞类型的比例正常。
