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肌肉与骨骼的关系:方法与管理——糖原贮积病的视角

The muscle-bone relationship: methods and management - perspectives in glycogen storage disease.

作者信息

Schönau Eckhard, Schwahn Bernd, Rauch Frank

机构信息

Children's Hospital, University of Cologne, Josef-Stelzmann-Strasse 9, 50924 Cologne, Germany.

出版信息

Eur J Pediatr. 2002 Oct;161 Suppl 1:S50-2. doi: 10.1007/s00431-002-1003-z. Epub 2002 Sep 5.

Abstract

UNLABELLED

Currently bone development is commonly presented as a process leading to the 'accumulation of peak bone mass'. Consequently, the usual approach to a suspected bone disorder in a child is to address the question are this child's bones as heavy as those of a healthy child of the same sex and age? However, from a functional perspective the aim of bone development should not be make bones as heavy as possible but to make them as stable as necessary. A functionally oriented approach should address two different questions: how strong are the bones? are they as strong as they need to be? It is clear that the bone has to be strong enough to withstand the mechanical forces to which it is exposed.

CONCLUSION

since the main forces applied to bones are due to muscle action, the strength of a bone should be related to the force of the muscles attached to it.

摘要

未标注

目前,骨骼发育通常被描述为一个导致“峰值骨量积累”的过程。因此,对于疑似患有骨骼疾病的儿童,通常的做法是解决这个问题:这个孩子的骨骼是否与同龄同性别的健康儿童一样重?然而,从功能的角度来看,骨骼发育的目标不应是使骨骼尽可能重,而是使其具备必要的稳定性。一种以功能为导向的方法应解决两个不同的问题:骨骼有多强壮?它们是否强壮到所需程度?显然,骨骼必须足够强壮以承受其所承受的机械力。

结论

由于作用于骨骼的主要力量来自肌肉活动,骨骼的强度应与附着于其上的肌肉力量相关。

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