Småbrekke Lars, Berild Dag, Giaever Anton, Myrbakk Torni, Fuskevåg Airin, Ericson Johanna U, Flaegstad Trond, Olsvik Orjan, Ringertz Signe H
Regional Drug Information Centre, Tromsø University Hospital, Norway.
Scand J Infect Dis. 2002;34(9):657-9. doi: 10.1080/00365540210147651.
We used a controlled before-and-after design with the aims of reducing both the total consumption of antibiotics and the use of broad-spectrum antibiotics against acute otitis media (AOM), and to study to what extent prescriptions for antibiotics against AOM were dispensed. Information on evidence-based treatment of uncomplicated AOM was provided to doctors and nurses, and written guidelines were implemented. Pamphlets and oral information concerning symptomatic treatment and the limited effect of antibiotic use in AOM were given to parents. Eligible patients were 819 children aged 1-15 y. The proportion of patients receiving a prescription for antibiotics was reduced from 90% at baseline to 74% during the study period. The proportion of prescriptions for penicillin V increased from 72% at baseline to 85% during the study period. There were no significant changes at the control site. The proportion of dispensed prescriptions was 70% both at baseline and during the study period. Educational efforts reduced the total consumption of antibiotics and the use of broad-spectrum antibiotics for AOM in children aged 1-15 y at an emergency call service. Data on antibiotic use in AOM based only on prescribing overestimates the use of antibiotics.
我们采用了前后对照设计,旨在减少急性中耳炎(AOM)抗生素的总消耗量以及广谱抗生素的使用,并研究针对AOM的抗生素处方配药情况。向医生和护士提供了关于单纯性AOM循证治疗的信息,并实施了书面指南。向家长发放了有关对症治疗以及抗生素在AOM中作用有限的宣传册和口头信息。符合条件的患者为819名1至15岁的儿童。研究期间,接受抗生素处方的患者比例从基线时的90%降至74%。青霉素V处方比例从基线时的72%增至研究期间的85%。对照地点无显著变化。基线时和研究期间的配药处方比例均为70%。教育措施减少了1至15岁儿童在急救服务中AOM抗生素的总消耗量以及广谱抗生素的使用。仅基于处方的AOM抗生素使用数据高估了抗生素的使用情况。