Go Tohshin, Nakamura Kenji
Department of Paediatrics, Otsu Red Cross Hospital, Otsu, Japan.
Eur J Paediatr Neurol. 2002;6(4):221-3. doi: 10.1053/ejpn.2002.0597.
A 15-month-old girl developed frequent seizures at the eruptive stage of exanthema subitum. The eruption persisted for 2 weeks. Serum immunoglobulin G antibody to human herpes virus type 6 (HHV-6) increased markedly. Interleukin-6 was elevated whereas HHV-6 deoxyribonucleic acid was not detected in cerebrospinal fluid. These findings suggest that immune-mediated reactions after HHV-6 infection rather than direct action of active HHV-6 are responsible for frequent seizures in this case.
一名15个月大的女童在幼儿急疹出疹期出现频繁惊厥。皮疹持续了2周。血清抗人疱疹病毒6型（HHV-6）免疫球蛋白G抗体显著升高。白细胞介素-6升高，而脑脊液中未检测到HHV-6脱氧核糖核酸。这些发现表明，在该病例中，HHV-6感染后的免疫介导反应而非活跃的HHV-6的直接作用是导致频繁惊厥的原因。
