Kim Dal Soo, Kim Jae Keon, Yoo Do Sung, Huh Phil Woo, Cho Kyuong Suck, Kang Joon Ki
Department of Neurosurgery, Uijongbu St. Mary 's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea.
J Korean Med Sci. 2002 Oct;17(5):695-8. doi: 10.3346/jkms.2002.17.5.695.
Takayasu's arteritis is a chronic inflammatory disease that produces a narrowing of the aorta and its major branches. Fibrosis and thickening of the arterial wall often occur in later stages, resulting in a cerebrovascular accident. The authors report two young women patients who presented with subarachnoid hemorrhage (SAH) and occlusive cerebrovasular disease associated with Takayasu's arteritis. Both patients had sudden headache and hemiparesis. Physical examination showed weak radial pulse, carotid bruit, and asymmetrical blood pressure. Erythrocyte sedimentation rate (ESR) was elevated in both patients. SAH was confirmed by brain computerized tomography (CT) or lumbar puncture. Occlusive cerebrovascular disease was diagnosed by brain magnetic resonance imaging (MRI), brain magnetic resonance angiography (MRA), and cerebral angiography. The findings of aortography and cerebral angiography were compatible with Takayasu's arteritis, but intracranial aneurysm was not found in either patient.
高安动脉炎是一种慢性炎症性疾病,可导致主动脉及其主要分支狭窄。动脉壁的纤维化和增厚常发生在疾病后期,从而引发脑血管意外。作者报告了两名年轻女性患者,她们表现为蛛网膜下腔出血(SAH)以及与高安动脉炎相关的闭塞性脑血管疾病。两名患者均突发头痛和偏瘫。体格检查显示桡动脉搏动减弱、颈动脉杂音和血压不对称。两名患者的红细胞沉降率(ESR)均升高。通过脑部计算机断层扫描(CT)或腰椎穿刺确诊为SAH。通过脑部磁共振成像(MRI)、脑部磁共振血管造影(MRA)和脑血管造影诊断为闭塞性脑血管疾病。主动脉造影和脑血管造影的结果与高安动脉炎相符,但两名患者均未发现颅内动脉瘤。