Sonwalkar H A, Gupta A K, Purkayastha S, Bodhey N K, Krishnamoorthy T
Department of Radiology, Sree Chithra Institute of Medical Science and Technology, Trivandrum, India -
Interv Neuroradiol. 2004 Sep 30;10(3):249-52. doi: 10.1177/159101990401000307. Epub 2005 Jan 5.
A rare case of multiple cerebral aneurysms associated with Takayasu aortitis is reported. Only seven cases have been reported so far, all of which are from Japan. This is the first case with this association being reported from India. A 50-year-old hypertensive woman developed sudden onset severe headache and loss of consciousness. CT scan revealed subarachnoid haemorrhage in the suprasellar cisterns and mild hydrocephalus. The patient on admission had a rebleed producing a massive subarachnoid haemorrhage. Angiogram revealed occlusion of bilateral vertebral arteries and right common carotid artery. The left carotid artery was ectatic with saccular aneurysms in the ophthalmic segment and communicating segment. Aortogram showed the radiological picture of Takayasu arteritis Type III. Surgical clipping of the aneurysms was performed. However, the patient developed a massive right cerebral infarct in the postoperative period following which she expired. Abnormal haemodynamics in the overloaded cerebral circulation rather than primary arteritic involvement of intracranial vessels appears to be the cause of aneurysm formation.
本文报道了一例罕见的多发性脑动脉瘤合并高安动脉炎的病例。迄今为止,仅报道过7例,均来自日本。这是印度首次报道的此类关联病例。一名50岁的高血压女性突发严重头痛并失去意识。CT扫描显示鞍上池蛛网膜下腔出血及轻度脑积水。患者入院时再次出血,导致大量蛛网膜下腔出血。血管造影显示双侧椎动脉及右颈总动脉闭塞。左侧颈动脉扩张,眼段及交通段有囊状动脉瘤。主动脉造影显示为III型高安动脉炎的影像学表现。对动脉瘤进行了手术夹闭。然而,患者术后出现大面积右脑梗死,随后死亡。颅内血管循环超负荷导致的异常血流动力学而非原发性动脉炎累及似乎是动脉瘤形成的原因。