Zellmer Sebastian
Labsoft Diagnostics AG, Robert-Franz-Ring 21, 06108 Halle, Germany.
Cell Mol Biol Lett. 2002;7(3):885-8.
Liposomes were incubated with an extract of human plantar stratum corneum. The liposomal lipids were hydrolysed, if composed of soy-bean phosphatidylcholine or phosphatidylglycerol. Rigid lipids were not degraded. The temperature optimum of the hydrolysis was between 30-35degC. CaCl enhanced, while EDTA reduced the rate of hydrolysis, indicating that the hydrolysis is due to a phospholipase A(2).
脂质体与人足底角质层提取物一起孵育。如果脂质体由大豆磷脂酰胆碱或磷脂酰甘油组成，其脂质会被水解。刚性脂质不会被降解。水解的最适温度在30至35摄氏度之间。氯化钙会提高水解速率，而乙二胺四乙酸（EDTA）会降低水解速率，这表明水解是由磷脂酶A2引起的。
