Palva T, Jokinen K, Saloheimo M, Karvonen P
ORL J Otorhinolaryngol Relat Spec. 1975;37(5):306-11. doi: 10.1159/000275239.
A method of utilizing an ultrasonic nebulizer (De Vilbiss 35 A) in local anesthesia for bronchoscopy is described. 10 ml of 4% Licocaine without adrenaline was used as anesthetic agent. Blood levels of Lidocaine were determined on 12 patients. The maximum blood levels were reached 6-8 min after the end of anesthesia. Blood lelvels ranged from 0.37 to 3.28 mug/ml being so in the nontoxic dosage range. A satisfactory anesthesia was achieved in 95% of the 1,043 patients subjected to bronchoscopy, while 5% felt that laryngeal anesthesia was not complete. In no case was it necessary to use the conventional way to complete the anesthesia. Nebulizer anesthesia was preferred by 100 persons who had been anesthetized by both the conventional method and the ultrasonic technique.
本文描述了一种在支气管镜检查局部麻醉中使用超声雾化器（德维比斯35A）的方法。使用10毫升不含肾上腺素的4%利多卡因作为麻醉剂。对12例患者测定了利多卡因的血药浓度。麻醉结束后6 - 8分钟达到最高血药浓度。血药浓度范围为0.37至3.28微克/毫升，处于无毒剂量范围内。在接受支气管镜检查的1043例患者中，95%获得了满意的麻醉效果，而5%的患者感觉喉麻不完善。在任何情况下都无需采用传统方法来完成麻醉。100名曾接受过传统方法和超声技术麻醉的患者更倾向于雾化器麻醉。
