伴有t(8;16)(p11;p13)的急性髓系白血病的逆转录聚合酶链反应分析：一种新型MOZ/CBP转录本的鉴定及CBP/MOZ表达缺失 - Suppr

RT-PCR analysis of acute myeloid leukemia with t(8;16)(p11;p13): identification of a novel MOZ/CBP transcript and absence of CBP/MOZ expression.

作者信息

Panagopoulos Ioannis, Fioretos Thoas, Isaksson Margareth, Mitelman Felix, Johansson Bertil, Theorin Niklas, Juliusson Gunnar

出版信息

Genes Chromosomes Cancer. 2002 Dec;35(4):372-4. doi: 10.1002/gcc.10131.

DOI:10.1002/gcc.10131

PMID:12378533

Abstract

摘要

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RT-PCR analysis of acute myeloid leukemia with t(8;16)(p11;p13): identification of a novel MOZ/CBP transcript and absence of CBP/MOZ expression.伴有t(8;16)(p11;p13)的急性髓系白血病的逆转录聚合酶链反应分析：一种新型MOZ/CBP转录本的鉴定及CBP/MOZ表达缺失

Genes Chromosomes Cancer. 2002 Dec;35(4):372-4. doi: 10.1002/gcc.10131.

MYST3/CREBBP (MOZ/CBP) and CREBBP/MYST3 (CBP/MOZ) transcripts in AML with t(8;16)(p11;p13).伴有t(8;16)(p11;p13)的急性髓系白血病中的MYST3/CREBBP（MOZ/CBP）和CREBBP/MYST3（CBP/MOZ）转录本

Genes Chromosomes Cancer. 2005 Feb;42(2):207-8; author reply 209. doi: 10.1002/gcc.20112.

Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13).急性髓系白血病中MOZ/CBP和CBP/MOZ嵌合体的基因组特征表明，损伤修复机制参与了t(8;16)(p11;p13)的起源。

Genes Chromosomes Cancer. 2003 Jan;36(1):90-8. doi: 10.1002/gcc.10137.

RT-PCR analysis of the MOZ-CBP and CBP-MOZ chimeric transcripts in acute myeloid leukemias with t(8;16)(p11;p13).对伴有t(8;16)(p11;p13)的急性髓系白血病中MOZ-CBP和CBP-MOZ嵌合转录本的逆转录聚合酶链反应分析

Genes Chromosomes Cancer. 2000 Aug;28(4):415-24. doi: 10.1002/1098-2264(200008)28:4<415::aid-gcc7>3.0.co;2-i.

RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications.伴有t(8;16)(p11;p13)的急性髓系白血病的逆转录聚合酶链反应和荧光原位杂交分析以及嵌合型MOZ和CBP转录本：断裂点簇区域及临床意义

Leukemia. 2004 Jun;18(6):1115-21. doi: 10.1038/sj.leu.2403353.

Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13).急性髓系白血病伴t(10;16)(q22;p13)时MORF和CBP基因的融合

Hum Mol Genet. 2001 Feb 15;10(4):395-404. doi: 10.1093/hmg/10.4.395.

A case of inv(8)(p11q24) associated with acute myeloid leukemia involves the MOZ and CBP genes in a masked t(8;16).一例与急性髓系白血病相关的inv(8)(p11q24)，在隐匿性t(8;16)中涉及MOZ和CBP基因。

Genes Chromosomes Cancer. 1999 Oct;26(2):161-5.

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein.急性髓系白血病的t(8;16)(p11;p13)易位将一种假定的乙酰转移酶与CREB结合蛋白融合。

Nat Genet. 1996 Sep;14(1):33-41. doi: 10.1038/ng0996-33.

Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation.I型MOZ/CBP（MYST3/CREBBP）是急性髓系白血病伴t(8;16)(p11;p13)易位中最常见的嵌合转录本。

Genes Chromosomes Cancer. 2004 Jun;40(2):140-5. doi: 10.1002/gcc.20022.

Spontaneous remission of adult acute myeloid leukemia with t(8;16)(p11;p13)/MOZ-CBP fusion.

Leuk Lymphoma. 2018 Jan;59(1):253-255. doi: 10.1080/10428194.2017.1320712. Epub 2017 May 23.

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De novo monocytic-M5b AML with t(8;16) (p11.2; p13.3) KAT6A/CREBBP fusion and FLT3-TKD mutation complicated by chemotherapy-induced Takotsubo cardiomyopathy.伴有t(8;16)(p11.2;p13.3) KAT6A/CREBBP融合及FLT3-TKD突变的新发单核细胞M5b型急性髓系白血病，并发化疗诱导的应激性心肌病。

BMJ Case Rep. 2023 Mar 28;16(3):e253812. doi: 10.1136/bcr-2022-253812.

Comparison between karyotyping-FISH-reverse transcription PCR and RNA-sequencing-fusion gene identification programs in the detection of KAT6A-CREBBP in acute myeloid leukemia.急性髓系白血病中KAT6A-CREBBP检测的核型分析-荧光原位杂交-逆转录聚合酶链反应与RNA测序-融合基因鉴定程序的比较

PLoS One. 2014 May 5;9(5):e96570. doi: 10.1371/journal.pone.0096570. eCollection 2014.

Lineage switch at relapse of childhood acute leukemia: a report of four cases.儿童急性白血病复发时的谱系转换：四例报告。

J Korean Med Sci. 2011 Jun;26(6):829-31. doi: 10.3346/jkms.2011.26.6.829. Epub 2011 May 18.

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RT-PCR analysis of acute myeloid leukemia with t(8;16)(p11;p13): identification of a novel MOZ/CBP transcript and absence of CBP/MOZ expression.

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