Th2 mediated regulation in RA and the spondyloarthropathies.
作者信息
van Roon J A G, Bijlsma J W J
机构信息
UMC Utrecht, The Netherlands.
出版信息
Ann Rheum Dis. 2002 Nov;61(11):951-4. doi: 10.1136/ard.61.11.951.
Abstract
摘要
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Atopic disorders in ankylosing spondylitis and rheumatoid arthritis.强直性脊柱炎和类风湿关节炎中的特应性疾病。
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Anti-TNF-alpha therapy for ankylosing spondylitis--a specific or nonspecific treatment?抗肿瘤坏死因子-α治疗强直性脊柱炎——一种特异性还是非特异性治疗？
N Engl J Med. 2002 May 2;346(18):1399-400. doi: 10.1056/NEJM200205023461811.
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Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells.分泌转化生长因子β的Th3调节性细胞的诱导及作用机制
Immunol Rev. 2001 Aug;182:207-14. doi: 10.1034/j.1600-065x.2001.1820117.x.
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Comorbidity and lifestyle, reproductive factors, and environmental exposures associated with rheumatoid arthritis.与类风湿性关节炎相关的合并症、生活方式、生殖因素及环境暴露
Ann Rheum Dis. 2001 Oct;60(10):934-9. doi: 10.1136/ard.60.10.934.
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Impaired Th1 cytokine production in spondyloarthropathy is restored by anti-TNFalpha.抗TNFα可恢复脊柱关节炎中Th1细胞因子产生受损的情况。
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Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population.人无反应性/抑制性CD4(+)CD25(+) T细胞：一个高度分化且易于凋亡的群体。
Eur J Immunol. 2001 Apr;31(4):1122-31. doi: 10.1002/1521-4141(200104)31:4<1122::aid-immu1122>3.0.co;2-p.
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Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis.白细胞介素-4与白细胞介素-10在类风湿关节炎炎症抑制及关节破坏中的协同作用
Arthritis Rheum. 2001 Jan;44(1):3-12. doi: 10.1002/1529-0131(200101)44:1<3::AID-ANR2>3.0.CO;2-U.
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Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism.强直性脊柱炎中肿瘤坏死因子α和干扰素γ的低T细胞产生：其与HLA - B27的关系及肿瘤坏死因子-308基因多态性的影响
Ann Rheum Dis. 2001 Jan;60(1):36-42. doi: 10.1136/ard.60.1.36.
9
Differential Th1/Th2 cytokine patterns in chronic arthritis: interferon gamma is highly expressed in synovium of rheumatoid arthritis compared with seronegative spondyloarthropathies.慢性关节炎中Th1/Th2细胞因子模式的差异：与血清阴性脊柱关节病相比，类风湿关节炎滑膜中γ干扰素高度表达。
Ann Rheum Dis. 2000 Apr;59(4):263-8. doi: 10.1136/ard.59.4.263.
10
Reduced expression of the regulatory CD4+ T cell subset is related to Th1/Th2 balance and disease severity in rheumatoid arthritis.调节性CD4 + T细胞亚群的表达降低与类风湿关节炎中的Th1/Th2平衡及疾病严重程度相关。
Arthritis Rheum. 2000 Mar;43(3):617-27. doi: 10.1002/1529-0131(200003)43:3<617::AID-ANR19>3.0.CO;2-B.
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