Sasse D, Schenk A
Acta Anat (Basel). 1975;93(1):78-87.
The reconstruction of the liver parenchyma of a golden hamster after poisoning with allyl formate is described. Allyl formate primarily destroys the periportal areas and leads, following the microvascularisation of the liver parenchyma, to a necrosis of the hepatocytes progressing towards the terminal hepatic venule. The still intact parenchymal zones can be characterized by the positive PAS reaction. In this study the preterminal and the terminal portal branches as well as zone 3, situated in the vasculatory periphery, were reconstructed. By this method, a three-dimensional presentation of the acinar functional zones was possible for the first time.
描述了甲酸烯丙酯中毒后金黄仓鼠肝实质的重建情况。甲酸烯丙酯主要破坏门周区域，并在肝实质微血管化后导致肝细胞坏死，坏死向终末肝静脉发展。仍完整的实质区域可通过阳性PAS反应来表征。在本研究中，重建了终末前和终末门静脉分支以及位于血管外周的3区。通过这种方法，首次实现了腺泡功能区的三维呈现。
