Gessesse M, Chali D, Wolde-Tensai B, Ergete W
Department of Paediatrics, Yekatit 12 Hospital, P.O. Box 257, Addis Ababa, Ethiopia.
Ethiop Med J. 2001 Oct;39(4):341-8.
A patient with diabetic ketoacidosis admitted for treatment developed features characteristic of rhinocerebral mucormycosis, confirmed by histopathologic examination, is presented. The patient had been experiencing symptoms of diabetes for one month before presentation to the hospital in state of diabetic ketoacidosis. Within a few days of admission he developed mucormycosis of the nasal cavity and the orbit which extended to the brain very fast and resulted in death. High index of suspicion form the clinical presentation in an immunocompromised patient, especially, one with diabetic ketoacidosis, is suggested to effect early intervention.
本文介绍了一名因糖尿病酮症酸中毒入院治疗的患者，其出现了鼻脑毛霉菌病的特征性表现，并经组织病理学检查确诊。该患者在以糖尿病酮症酸中毒状态入院前一个月就已出现糖尿病症状。入院后几天内，他就患上了鼻腔和眼眶毛霉菌病，且很快蔓延至脑部，最终导致死亡。对于免疫功能低下的患者，尤其是患有糖尿病酮症酸中毒的患者，建议从临床表现中保持高度怀疑指数，以便进行早期干预。
