Lumia A R, Westervelt M O, Rieder C A
J Comp Physiol Psychol. 1975 Nov;89(9):1091-9. doi: 10.1037/h0078152.
Male Mongolian gerbils, selected for high marking frequency, were paired with male opponents, and marking and fighting behavior were recorded. Animals then underwent castration, bilateral bulbectomy, unilateral bulbectomy, the combined operations, or a sham operation; and their behavior was again observed. All operated animals showed drastic reduction in both marking and aggressive encounters. Injections of testosterone propionate (TP) produced complete restoration of marking in castrates, but not in bilaterally or unilaterally bulbectomized animals or combined operates. The exhibition of aggression after injections of TP, however, was enhanced to supernormal levels in bulbectomized or bulbectomized-castrated animals. The results suggest the following: that removal of the olfactory bulbs may eliminate a critical neural input necessary for the normal expression of marking and agonistic; that although marking and fighting are influences by olfactory input and gonadal steroids, their regulatory mechanisms may not be identical; and that removal of the bulbs may sensitize a neural mechanism controlling aggression, thus potentiating its elicitation following administration of exogenous androgen.
选择标记频率高的雄性蒙古沙鼠与雄性对手配对，并记录标记和战斗行为。然后对动物进行去势、双侧嗅球切除术、单侧嗅球切除术、联合手术或假手术；再次观察它们的行为。所有接受手术的动物在标记和攻击性遭遇方面均表现出大幅减少。注射丙酸睾酮（TP）可使去势动物的标记行为完全恢复，但在双侧或单侧嗅球切除的动物或接受联合手术的动物中则不然。然而，在嗅球切除或嗅球切除 - 去势的动物中，注射TP后的攻击行为表现增强至超常水平。结果表明：切除嗅球可能消除了标记和争斗正常表达所需的关键神经输入；尽管标记和战斗受嗅觉输入和性腺类固醇的影响，但其调节机制可能不同；切除嗅球可能使控制攻击的神经机制敏感化，从而在给予外源性雄激素后增强其诱发。
