Demisch K, Magnet W, Neubauer M, Schöffling K
Dtsch Med Wochenschr. 1975 May 16;100(20):1117-23. doi: 10.1055/s-0028-1106344.
109 women with hirsutism were investigated (102 with idiopathic hirsutism, four with Stein-Leventhal syndrome, one each with adrenal adenoma, adrenal carcinoma and hilus-cell tumour). Levels of testosterone, dihydrotestosterone, androstenediol and dehydroepiandrosterone were measured, usually in the course of a combined adrenal-ovarian stimulation-suppression test. Measuring several plasma androgens made it possible to distinguish idiopathic hirsutism from other endocrine diseases with hirsutism. Mean plasma testosterone level in idiopathic hirsutism was not significantly different from that in healthy women. Elevated testosterone and(or) dihydrotestosterone levels were found in only 22 of 102 women. There was a marked increase in plasma testosterone after HCG injection in the patient with Stein-Leventhal syndrome. Androstenediol and dehydroepiandrosterone were both important in the diagnosis of autonomous adrenal steroid secretion.
对109例多毛症女性进行了调查（102例特发性多毛症，4例斯坦因-莱文塔尔综合征，1例肾上腺腺瘤、1例肾上腺皮质癌和1例卵巢门细胞瘤）。通常在肾上腺-卵巢联合刺激-抑制试验过程中测量睾酮、双氢睾酮、雄烯二醇和脱氢表雄酮水平。检测多种血浆雄激素有助于鉴别特发性多毛症与其他伴有多毛症的内分泌疾病。特发性多毛症患者的平均血浆睾酮水平与健康女性无显著差异。102例女性中仅22例睾酮和（或）双氢睾酮水平升高。斯坦因-莱文塔尔综合征患者注射人绒毛膜促性腺激素（HCG）后血浆睾酮显著升高。雄烯二醇和脱氢表雄酮在自主性肾上腺类固醇分泌的诊断中均具有重要意义。
