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[多囊卵巢综合征所致多毛性男性化与肾上腺皮质多毛症的鉴别诊断]

[The differential diagnosis of hairy virilism in polycystic ovaries from adrenal cortical hirsutism].

作者信息

Maleeva A, Milkov V, Visheva N, Kekhaĭova M

出版信息

Vutr Boles. 1990;29(3):93-9.

PMID:2178292
Abstract

The hormones on the axis hypophysis-ovary and hypophysis-suprarenal gland were examined in 60 women with polycystic ovaries and hairy virilism, 53 women with hirsutism and 45 healthy women, all of the same age. The results show that in hairy virilism from ovarian origin the luteinizing hormone level (LH) is increased 100% and the follicle stimulating hormone level (FSH) is decreased 200%. The index LH/FSH is increased more than 3 times. The testosterone and androstanedione levels are increased, too. In patients with suprarenal-cortex hirsutism the levels of ACTH, androstanedione, dehydroepiandrosterone-sulfate, testosterone and cortisol are increased. A hirsutism from running with hyperprolactinemia is differentiated. The three hirsutism forms may appear as separate forms or in combination.

摘要

对60名患有多囊卵巢和多毛男性化的女性、53名患有多毛症的女性以及45名年龄相同的健康女性,检测了垂体 - 卵巢轴和垂体 - 肾上腺轴的激素。结果显示,源于卵巢的多毛男性化患者,促黄体生成素(LH)水平升高100%,促卵泡生成素(FSH)水平降低200%。LH/FSH指数升高超过3倍。睾酮和雄烯二酮水平也升高。肾上腺皮质多毛症患者的促肾上腺皮质激素(ACTH)、雄烯二酮、硫酸脱氢表雄酮、睾酮和皮质醇水平升高。区分了伴有高催乳素血症的多毛症。这三种多毛症形式可能单独出现或合并出现。

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