Pillet P, Boralévi F, Chateil J F, Pinlou E, Lacombe D
Service de pédiatrie générale et rhumatologie pédiatrique, hôpital Pellegrin-Enfants, place Amélie-Raba-Léon, 33076 Bordeaux, France.
Arch Pediatr. 2002 Sep;9(9):921-4. doi: 10.1016/s0929-693x(02)00024-6.
Two brothers with a Currarino's disease are reported. Patients characteristics included a dysmorphic syndrome, cranial suture defects, hypertrophic osteoarthropathy and severe chronic eczema.
Consanguinity of parents suggests an autosomal recessive inheritance.
Currarino's disease is a rare unknown constitutional syndrome. The age of beginning of the disease, the cranial suture defects and the chronic eczema allow to distinguish it from the others primary hypertrophic osteoarthropathies.
报道了两兄弟患库拉里诺病。患者特征包括畸形综合征、颅骨缝缺损、肥大性骨关节病和严重慢性湿疹。
父母近亲结婚提示常染色体隐性遗传。
库拉里诺病是一种罕见的不明先天性综合征。该病的发病年龄、颅骨缝缺损和慢性湿疹使其有别于其他原发性肥大性骨关节病。
