Reginato A J, Schiapachasse V, Guerrero R
Skeletal Radiol. 1982;8(2):105-9. doi: 10.1007/BF00349574.
Three children with idiopathic hypertrophic osteoarthropathy and cranial suture defects are reported. The syndrome was recognized after birth and in the two oldest siblings, the cranial defects and subperiosteal bone formation resolved almost completely by age 4 and 6 years. The joint swelling and clubbing persisted and mild bone reabsorption of the distal phalanges became apparent at an older age. Two siblings and both parents had normal bone X-rays and no clubbing. This study confirms the association of cranial sutural defects and familial idiopathic hypertrophic osteoarthropathy.
报告了3例患有特发性肥厚性骨关节病和颅骨缝缺损的儿童。该综合征在出生后被发现，在两个年龄较大的兄弟姐妹中，颅骨缺损和骨膜下骨形成在4岁和6岁时几乎完全消失。关节肿胀和杵状指持续存在，远端指骨的轻度骨质吸收在较大年龄时变得明显。两个兄弟姐妹和父母的骨骼X线检查均正常，无杵状指。本研究证实了颅骨缝缺损与家族性特发性肥厚性骨关节病之间的关联。
