Postnov I V
Kardiologiia. 1975 Aug;15(8):18-23.
A hypothesis is presented that suggests that essential hypertension and its analog -- spontaneous hypertension in rats originates from a genetically determined defect of the permeability of the cell membranes. An increasing permeability of the membranes for potassium and sodium may serve as a common cause of activation of the servomechanisms that provide for the elevation of the arterial blood pressure. A chronic psychoemotional stress, salt or corticosteroid overloading are the conditions that display a latent membranous insufficiency.
提出了一种假说，认为原发性高血压及其类似物——大鼠自发性高血压起源于遗传决定的细胞膜通透性缺陷。细胞膜对钾和钠通透性的增加可能是导致动脉血压升高的伺服机制激活的共同原因。慢性心理情绪应激、盐负荷过重或皮质类固醇负荷过重是表现出潜在膜功能不全的情况。
