Jakobsson Karl-Erik, Petruson Björn, Lindblom Bertil
Section of Neurological Diseases, Institute of Clinical Neuroscience, The Sahlgrenska Academy at Gothenburg University, Sweden.
Acta Ophthalmol Scand. 2002 Oct;80(5):512-6. doi: 10.1034/j.1600-0420.2002.800510.x.
To study early visual restoration following surgical removal of pituitary adenomas compressing the optic chiasm.
Eleven patients were examined with high-pass resolution perimetry (HRP) before and after trans-sphenoidal adenomectomy. Visual fields were examined on the second postoperative day. The result was interpreted in terms of the estimated fraction of functioning retino-cortical connections.
In the upper and lower temporal visual field quadrants, the mean increases in the fraction of functioning neural channels were 19% (p < 0.001) and 17% (p = 0.001), respectively, on day 2 after surgery. These increased to 35% on day 12. The nasal hemifield showed no change on day 2, but functioning neural channels had increased by 15% on day 5 (p = 0.017). Mean visual acuity improved from 0.6 preoperatively to 1.0 on day 2 (p = 0.030) but did not change significantly thereafter.
All visual field sectors and visual acuity improved after surgery. Improvement starting in the temporal hemifield was already evident on the second postoperative day.
研究手术切除压迫视交叉的垂体腺瘤后的早期视觉恢复情况。
11例患者在经蝶窦腺瘤切除术前和术后接受了高通分辨率视野检查（HRP）。术后第二天检查视野。结果根据估计的功能性视网膜 - 皮质连接分数进行解释。
在手术术后第2天，颞侧视野上下象限中，功能性神经通道分数的平均增加分别为19%（p < 0.001）和17%（p = 0.001）。这些在术后第12天增加到35%。鼻侧半视野在术后第2天无变化，但在术后第5天功能性神经通道增加了15%（p = 0.017）。平均视力从术前的0.6提高到术后第2天的1.0（p = 0.030），但此后无显著变化。
术后所有视野扇形区和视力均有改善。术后第二天颞侧半视野的改善就已明显。
