Stoelting R K, Peterson C
Anesth Analg. 1975 Nov-Dec;54(6):705-9. doi: 10.1213/00000539-197511000-00007.
The incidence of heart-rate slowing (greater than 15 percent) and junctional rhythm after two injections of succinylcholine (1 mg/kg), separated by 5 minutes, was determined in adult patients. All patients received intramuscular morphine as preanesthetic medication 60 to 90 minutes before intravenous thiamylal anesthetic induction. Intramuscular atropine (mcg/kg) 60 to 90 or 15 to 20 minutes before anesthetic induction did not alter the incidence of first or second succinylcholine dose heart-rate slowing or junctional rhythm as compared with patients receiving only morphine premedication.
在成年患者中,测定了间隔5分钟注射两次琥珀酰胆碱(1毫克/千克)后心率减慢(超过15%)和交界性心律的发生率。所有患者在静脉注射硫喷妥钠进行麻醉诱导前60至90分钟接受肌肉注射吗啡作为麻醉前用药。与仅接受吗啡预处理的患者相比,在麻醉诱导前60至90分钟或15至20分钟肌肉注射阿托品(微克/千克)并不会改变首次或第二次琥珀酰胆碱剂量导致的心率减慢或交界性心律的发生率。