Schultz G A, Browder L W
Biochem Genet. 1975 Oct;13(9-10):663-71. doi: 10.1007/BF00484924.
Unfertilized eggs and early embryos up to the 2-day (16-cell) cleavage stage of development in the rabbit contain predominantly the most cathodal lactate dehydrogenase isoenzyme made up of A-type subunits. Following early cleavage there is a progressing increase in total LDH activity in the embryo as development proceeds through 4- and 6-day blastocyst stages. This is accompanied by an increase in the amount of B-type subunits and a concomitant shift in the lactate dehydrogenase isoenzyme electrophoretic pattern toward the anodal isoenzyme types.
未受精的兔卵以及发育至2天（16细胞）卵裂期的早期胚胎主要含有由A型亚基组成的最阴极的乳酸脱氢酶同工酶。在早期卵裂之后，随着胚胎发育至4天和6天的囊胚期，胚胎中的总乳酸脱氢酶活性持续增加。这伴随着B型亚基数量的增加以及乳酸脱氢酶同工酶电泳图谱向阳极同工酶类型的相应转变。
