Chen Andrew L, Joseph Thomas N, Wolinksy Phillip R, Tejwani Nirmal C, Kummer Frederick J, Egol Kenneth A, Koval Kenneth J
Musculoskeletal Research Institute, Hospital for Joint Diseases Orthopaedic Institute New York, New York 10033, USA.
J Trauma. 2002 Oct;53(4):733-7. doi: 10.1097/00005373-200210000-00019.
This study compared the fixation stability of two treatments for humeral shaft fractures with segmental bone loss during cyclic, physiologic loading.
Six matched pairs of human humeri received either a 10-hole broad dynamic compression plate or a locked antegrade inserted humeral nail applied to a humeral diaphyseal osteotomy with a 1.5-cm gap defect. The bone-implant humeral constructs were axially loaded for 10,000 cycles at 250 N and 500 N, with measurements of gap displacement and calculation of construct stiffness. The specimens were then loaded to failure.
Cyclic loading showed no difference between the two groups for average gap displacement or construct stiffness. The intramedullary nail constructs failed by humeral shaft splitting (n = 4) or head cut-out (n = 2) at an average of 958.3 N, whereas the plate constructs failed by humeral shaft splitting and screw pull-out (n = 3) or plate bending (n = 3) at an average of 641.7 N (p < 0.001).
Although both methods offer similar fixation stability under physiologic loads, the higher load to failure demonstrated by intramedullary nail fixation may have implications for the patient with multiple injuries for whom partial weightbearing on the injured upper extremity may be necessary.
本研究比较了两种治疗肱骨干骨折合并节段性骨缺损的方法在周期性生理负荷下的固定稳定性。
六对匹配的人体肱骨,分别采用10孔宽动力加压钢板或锁定顺行插入式肱骨钉,应用于肱骨干截骨并造成1.5厘米间隙缺损的情况。将骨-植入物肱骨结构在250牛和500牛的轴向负荷下加载10000次循环,测量间隙位移并计算结构刚度。然后将标本加载至破坏。
循环加载显示两组在平均间隙位移或结构刚度方面无差异。髓内钉结构平均在958.3牛时因肱骨干劈裂(n = 4)或头部穿出(n = 2)而失效,而钢板结构平均在641.7牛时因肱骨干劈裂和螺钉拔出(n = 3)或钢板弯曲(n = 3)而失效(p < 0.001)。
虽然两种方法在生理负荷下提供相似的固定稳定性,但髓内钉固定所显示的更高破坏负荷可能对有多处损伤且可能需要在受伤上肢部分负重的患者有意义。