Vinoy S, Mascie-Taylor C G N, Rosetta L
Laboratoire de Physiologie des Adaptations, Faculté de Médecine Cochin Port-Royal, Paris, France.
Ann Hum Biol. 2002 Sep-Oct;29(5):488-94. doi: 10.1080/03014460110112051.
The betel-nut quid, a piece of areca nut chewed alone or mixed with tobacco and slaked lime wrapped in betel vine leaf, is widely used in Asian populations as a stimulant (due to the cholinergic agent, arecoline) or as a relaxant (due to arecaidine and guvacine).
This study, which formed part of a larger project assessing the effect of energy expenditure on the duration of post-partum amenorrhoea, provided the opportunity to assess the role of chronic areca nut usage on heart rate and oxygen consumption during resting periods and during graded stepping tests.
The mothers (n = 47), all of whom were lactating, were aged between 19 and 39, of low nutritional status and anaemic and they all chewed betel quid daily.
Moderate users of betel quid (defined as more than 3 times a day) were found, on average, to have a significantly lower heart rate at rest and during exercise than low betel quid users (less than 3 times a day) but there was no modification in oxygen consumption.
Chronic betel quid use does not seem to affect the assessment of 24h energy expenditure provided that subjects are denied access to betel nut usage before and during calibration.
槟榔块，即单独咀嚼的槟榔果，或与烟草及裹在蒌叶中的熟石灰混合咀嚼的槟榔果，在亚洲人群中被广泛用作兴奋剂（由于胆碱能剂槟榔碱）或用作松弛剂（由于槟榔次碱和四氢烟酸）。
本研究是一项评估能量消耗对产后闭经持续时间影响的大型项目的一部分，提供了评估长期食用槟榔对静息期和分级踏车试验期间心率和耗氧量作用的机会。
母亲们（n = 47）均处于哺乳期，年龄在19至39岁之间，营养状况差且贫血，她们每天都咀嚼槟榔块。
发现槟榔块中度使用者（定义为每天超过3次）在静息和运动时的心率平均显著低于槟榔块低使用者（每天少于3次），但耗氧量没有变化。
如果在校准前和校准期间不让受试者食用槟榔果，长期食用槟榔块似乎不会影响24小时能量消耗的评估。
