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查尔斯·博内幻觉的神经基础:一种假说。

The neural basis of Charles Bonnet hallucinations: a hypothesis.

作者信息

Burke W

机构信息

Department of Physiology, University of Sydney, Australia.

出版信息

J Neurol Neurosurg Psychiatry. 2002 Nov;73(5):535-41. doi: 10.1136/jnnp.73.5.535.

Abstract

OBJECTIVES

To describe the hallucinations occurring as a result of a macular hole in each eye and to investigate the neural basis.

METHODS

Psychophysical observations including sketches of the hallucinations calibrated for size.

RESULTS

All the hallucinations were of the geometric (patterned) type and lasted for only a few days.

CONCLUSIONS

The observations can be explained on the basis of a "deafferentation" model, which is described in some detail. It is proposed that the hallucinations result from activation of the "blobs" of area V1 and the "stripes" of area V2 in the visual cortex. A theory is proposed to account for the disappearance of the hallucinations by a "filling in" mechanism.

摘要

目的

描述因每只眼睛黄斑裂孔而出现的幻觉,并研究其神经基础。

方法

进行心理物理学观察,包括按尺寸校准的幻觉草图。

结果

所有幻觉均为几何(图案)型,且仅持续数天。

结论

这些观察结果可以基于一种“传入神经阻滞”模型来解释,该模型将进行详细描述。提出幻觉是由视觉皮层中V1区的“斑点”和V2区的“条纹”激活所致。还提出了一种理论来解释通过“填补”机制幻觉消失的现象。

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