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同意角膜捐献:影响因素

Consenting to cornea donation: influencing factors.

作者信息

Krieglstein Tina R, Welge-Lüssen Ulrich C, Priglinger Siegfried, Kampik Anselm, Priemer Fritz, Neubauer Aljoscha S

机构信息

Department of Ophthalmology, Ludwig-Maximilians-Universität, Mathildenstr. 8, 80336, Munich, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2002 Oct;240(10):816-21. doi: 10.1007/s00417-002-0545-0. Epub 2002 Sep 20.

Abstract

BACKGROUND

The purpose of the study was to determine factors influencing the decision of the next relative being asked for consent to cornea donation in a prospective, non-comparative case series.

METHODS

Interviews with the relatives of 264 potential cornea donors to the eye bank of the Ludwig-Maximilians-Universität, Munich, were documented following a standardized protocol. The influence of sociological factors on the frequency of obtained consents was investigated by uni- and multivariate analysis.

RESULTS

During a 9-month period, 214 relatives of 264 possible donors were interviewed for consent to cornea donation. In total, 144 consents (67%) and 70 refusals (33%) were obtained; 50 relatives could not be reached. Analysis showed a higher consent rate for donors with a university degree (72%) versus those without (68%). Consent was more often obtained from relatives of donors that were divorced (71%) than from unmarried ones (63%). Husband and wife (71%) consented more frequently to cornea donation than children of age (62%) or parents (58%). Examination of residential area postal codes indicated more frequent refusals from donors of rural (56% consent rate) than urban Munich populations (67% consent rate). The situation was the opposite concerning the residential area of the consenting relative. Postal codes of both the donor and the relative were statistically significant factors in a multiple logistic regression model. There was relatively high willingness to donate in suicides (70%), but not significantly different from other causes like natural deaths (70%) and traffic accidents (66%).

CONCLUSIONS

Some socioeconomic factors such as - in particular - the permanent address of the potential donors and their relatives reflecting a different background and status play an important role in the willingness to donate. A better understanding of this decision making can help the physician to ask more empathically for consent and inform the public more specifically about the donation process.

摘要

背景

本研究的目的是在一个前瞻性、非对照病例系列中,确定影响要求下一位亲属同意角膜捐献决策的因素。

方法

按照标准化方案记录了对慕尼黑路德维希 - 马克西米利安大学眼库264名潜在角膜捐献者亲属的访谈情况。通过单因素和多因素分析研究社会学因素对获得同意频率的影响。

结果

在9个月期间,对264名可能捐献者中的214名亲属进行了角膜捐献同意访谈。总共获得了144份同意(67%)和70份拒绝(33%);50名亲属无法联系到。分析表明,具有大学学历的捐献者同意率(72%)高于无大学学历者(68%)。离婚捐献者的亲属比未婚捐献者的亲属更常获得同意(71%对63%)。夫妻(71%)比适龄子女(62%)或父母(58%)更频繁地同意角膜捐献。对居住地区邮政编码的检查表明,农村捐献者的拒绝率更高(同意率56%),而慕尼黑城市人口的同意率为67%。同意亲属的居住地区情况则相反。在多因素逻辑回归模型中,捐献者和亲属的邮政编码都是具有统计学意义的因素。自杀者的捐献意愿相对较高(70%),但与自然死亡(70%)和交通事故(66%)等其他原因相比无显著差异。

结论

一些社会经济因素,特别是潜在捐献者及其亲属的常住地址反映了不同的背景和地位,在捐献意愿中起着重要作用。更好地理解这一决策过程有助于医生更有同理心地面询同意,并更具体地向公众介绍捐献过程。

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