Krieglstein Tina R, Welge-Lüssen Ulrich C, Priglinger Siegfried, Kampik Anselm, Priemer Fritz, Neubauer Aljoscha S
Department of Ophthalmology, Ludwig-Maximilians-Universität, Mathildenstr. 8, 80336, Munich, Germany.
Graefes Arch Clin Exp Ophthalmol. 2002 Oct;240(10):816-21. doi: 10.1007/s00417-002-0545-0. Epub 2002 Sep 20.
The purpose of the study was to determine factors influencing the decision of the next relative being asked for consent to cornea donation in a prospective, non-comparative case series.
Interviews with the relatives of 264 potential cornea donors to the eye bank of the Ludwig-Maximilians-Universität, Munich, were documented following a standardized protocol. The influence of sociological factors on the frequency of obtained consents was investigated by uni- and multivariate analysis.
During a 9-month period, 214 relatives of 264 possible donors were interviewed for consent to cornea donation. In total, 144 consents (67%) and 70 refusals (33%) were obtained; 50 relatives could not be reached. Analysis showed a higher consent rate for donors with a university degree (72%) versus those without (68%). Consent was more often obtained from relatives of donors that were divorced (71%) than from unmarried ones (63%). Husband and wife (71%) consented more frequently to cornea donation than children of age (62%) or parents (58%). Examination of residential area postal codes indicated more frequent refusals from donors of rural (56% consent rate) than urban Munich populations (67% consent rate). The situation was the opposite concerning the residential area of the consenting relative. Postal codes of both the donor and the relative were statistically significant factors in a multiple logistic regression model. There was relatively high willingness to donate in suicides (70%), but not significantly different from other causes like natural deaths (70%) and traffic accidents (66%).
Some socioeconomic factors such as - in particular - the permanent address of the potential donors and their relatives reflecting a different background and status play an important role in the willingness to donate. A better understanding of this decision making can help the physician to ask more empathically for consent and inform the public more specifically about the donation process.
本研究的目的是在一个前瞻性、非对照病例系列中,确定影响要求下一位亲属同意角膜捐献决策的因素。
按照标准化方案记录了对慕尼黑路德维希 - 马克西米利安大学眼库264名潜在角膜捐献者亲属的访谈情况。通过单因素和多因素分析研究社会学因素对获得同意频率的影响。
在9个月期间,对264名可能捐献者中的214名亲属进行了角膜捐献同意访谈。总共获得了144份同意(67%)和70份拒绝(33%);50名亲属无法联系到。分析表明,具有大学学历的捐献者同意率(72%)高于无大学学历者(68%)。离婚捐献者的亲属比未婚捐献者的亲属更常获得同意(71%对63%)。夫妻(71%)比适龄子女(62%)或父母(58%)更频繁地同意角膜捐献。对居住地区邮政编码的检查表明,农村捐献者的拒绝率更高(同意率56%),而慕尼黑城市人口的同意率为67%。同意亲属的居住地区情况则相反。在多因素逻辑回归模型中,捐献者和亲属的邮政编码都是具有统计学意义的因素。自杀者的捐献意愿相对较高(70%),但与自然死亡(70%)和交通事故(66%)等其他原因相比无显著差异。
一些社会经济因素,特别是潜在捐献者及其亲属的常住地址反映了不同的背景和地位,在捐献意愿中起着重要作用。更好地理解这一决策过程有助于医生更有同理心地面询同意,并更具体地向公众介绍捐献过程。