Zacho A, Nielsen J, Cederqvist C
Acta Chir Scand. 1975;141(7):676-9.
The relationship between the type of tobacco used and the localization of the tumour was studied in 493 patients with gastric cancer. The relative frequency of tumour site was found to vary significantly with the type of tobacco. In men who used all kinds of tobacco, a pipe was the most common form of smoking. Women smoked only cheroots or cigarettes or both. Male smokers showed a significantly higher percentage of tumours at the cardia than did female smokers. Female smokers had a significantly higher percentage of tumours involving the entire stomach than male smokers. Male smokers with tumours at the cardia were significantly more often pipe smokers and cigarette smokers than cheroot smokers. Male smokers with tumours involving the entire stomach were significantly more often cheroot smokers than cigarette smokers. The localization of tumours in cigarette smokers differed in men and women, indicating that cigarette smoking per se possibly plays a subordinate causal role. On the other hand, the distribution pattern of the localization among cheroot smokers was practically the same in both sexes, which might indicate that this type of smoking plays an important role. The same probably applies to pipe smoking, especially when combined with snuff or chewing tobacco, but these types of tobacco had not been used by the women. It is mentioned that not only the nature of tobacco used, but also concurrent factors may influence the localization of the tumours.
对493例胃癌患者使用的烟草类型与肿瘤定位之间的关系进行了研究。发现肿瘤部位的相对频率随烟草类型的不同而有显著差异。在使用各类烟草的男性中，抽烟斗是最常见的吸烟方式。女性只抽雪茄或香烟，或两者都抽。男性吸烟者贲门处肿瘤的比例明显高于女性吸烟者。女性吸烟者全胃受累肿瘤的比例明显高于男性吸烟者。贲门处有肿瘤的男性吸烟者中，抽烟斗者和吸香烟者明显多于抽雪茄者。全胃受累的男性吸烟者中，抽雪茄者明显多于吸香烟者。吸烟者中肿瘤的定位在男性和女性中有所不同，这表明吸烟本身可能只起次要的因果作用。另一方面，抽雪茄者中肿瘤定位的分布模式在两性中几乎相同，这可能表明这种吸烟方式起着重要作用。抽烟斗可能也是如此，尤其是当与鼻烟或嚼烟一起使用时，但这些烟草类型女性并未使用。文中提到，不仅所使用烟草的性质，而且并发因素也可能影响肿瘤的定位。
