Lange P, Groth S, Nyboe J, Mortensen J, Appleyard M, Jensen G, Schnohr P
Medical Department B, Rigshospitalet, Copenhagen, Denmark.
Thorax. 1990 Jan;45(1):22-6. doi: 10.1136/thx.45.1.22.
Data from a five year follow up study on 4372 smokers and 3753 non-smokers were analysed to investigate the influence of the type of tobacco smoked and whether the subjects said they inhaled or not on the decline in forced expiratory volume in one second (FEV1). The study sample comprised 1492 smokers of plain cigarettes and 1936 smokers of filter cigarettes, 1711 smokers of cheroots or cigars, and 233 male pipe smokers. Over the five years, smokers, especially those who said that they inhaled, had a higher rate of decline of FEV1 than non-smokers, in whom the average decline in FEV1 was 25 ml/year for women and 30 ml/year for men. There was no significant difference in the decline in FEV1 between filter cigarette smokers and plain cigarette smokers. The decline in FEV1 in cigar or cheroot smokers was the highest for all the smoking groups, and associated with a very high tobacco consumption in this group. Among pipe smokers who inhaled, the decline in FEV1 was slightly higher than in the cigarette smokers, whereas non-inhaling pipe smokers had a decline in FEV1 that was similar to that of non-smokers. In general, the smokers who said that they did not inhale had a smaller decline in FEV1 than those who said that they did. The effect of inhalation varied in magnitude in different smoking groups, being most pronounced in pipe smokers.
对4372名吸烟者和3753名非吸烟者进行了一项为期五年的随访研究,分析所吸烟草类型以及受试者是否表示会吸入,对一秒用力呼气量(FEV1)下降的影响。研究样本包括1492名吸普通香烟的吸烟者、1936名吸过滤嘴香烟的吸烟者、1711名吸方头雪茄或雪茄烟的吸烟者以及233名男性烟斗吸烟者。在这五年中,吸烟者,尤其是那些表示会吸入的吸烟者,FEV1的下降率高于非吸烟者,非吸烟者中女性FEV1的平均下降率为每年25毫升,男性为每年30毫升。吸过滤嘴香烟的吸烟者和吸普通香烟的吸烟者在FEV1下降方面没有显著差异。在所有吸烟群体中,吸雪茄或方头雪茄烟的吸烟者FEV1下降幅度最大,且该群体烟草消费量非常高。在吸入的烟斗吸烟者中,FEV1的下降略高于吸卷烟者,而不吸入的烟斗吸烟者FEV1的下降与非吸烟者相似。总体而言,表示不吸入的吸烟者FEV1下降幅度小于表示会吸入的吸烟者。吸入的影响在不同吸烟群体中的程度各不相同,在烟斗吸烟者中最为明显。