Ohmori Keitaro, Masuda Kenichi, Sakaguchi Masahiro, Kaburagi Yukiko, Ohno Koichi, Tsujimoto Hajime
Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.
J Vet Med Sci. 2002 Sep;64(9):851-3. doi: 10.1292/jvms.64.851.
Adverse reactions to vaccines were examined in 311 canine cases reported to the Ministry of Agriculture, Forestry and Fisheries in Japan during the period of 6 years from April of 1994 to March of 2000, and classified according to their clinical symptoms. There were 27 cases of adverse reactions to rabies virus vaccines. Gastrointestinal symptoms were the most frequently observed (26%), followed by respiratory and/or cardiovascular symptoms (22%) and dermatologic symptoms (11%). There were 284 cases of adverse reactions to non-rabies monovalent vaccines and mixed vaccines. Dermatologic symptoms were the most frequently observed (53%), followed by gastrointestinal symptoms (16%) and respiratory and/or cardiovascular symptoms (14%). Of the total 311 cases, 11 (3.5%) died of adverse reactions to vaccines.
对1994年4月至2000年3月这6年间向日本农林水产省报告的311例犬类病例的疫苗不良反应进行了检查，并根据临床症状进行了分类。有27例狂犬病病毒疫苗不良反应病例。胃肠道症状最为常见（26%），其次是呼吸和/或心血管症状（22%）以及皮肤症状（11%）。有284例非狂犬病单价疫苗和混合疫苗不良反应病例。皮肤症状最为常见（53%），其次是胃肠道症状（16%）以及呼吸和/或心血管症状（14%）。在这311例病例中，有11例（3.5%）死于疫苗不良反应。
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