Glomerular ultrastructural abnormalities in a patient with mixed IgG-IgM essential cryoglobulinemic glomerulonephritis.

Distinct glomerular ultrastructural lesions in the form of nodular subepithelial and intramembranous, as well as discrete and band-like subendothelial deposits are described in a patient suffering from mixed IgG-IgM essential cyoglobulinemic glomerulonephritis. It is suggested that the deposits may represent immune complexes which are belived to play a central role in the pathogenesis of the glomerulonephritis.