Lukacs I
Minerva Med. 1975 Apr 14;66(28):1341-51.
Sebaceous gland activity in the newborn and children is extensive at first in the epidermis, and later decreases owing to defective operation of the sweat glands, circulation changes, growth of the hair, and a predisposition to infection, for which significant treatment is required. In addition to the genetic "typus neurodermiticus", pharmaceutical, alimentary and respiratory allergens and psychological factors may play a part in the appearance of atopical dermatitis. Onset is usually in the 2nd to 6th month and the side of the face and the scalp are affected. The clinical picture varies considerably with age and includes sanious foci covered with scabs on the head and eczema flexurarum. Differences in family history, age and the location of sites will distinguish this form from seborrhoeic dermatitis. Gluteal dermitis is secondary to congestion caused by dampness, rugging and soaking, and the action of stools and urine (bacterial amniogenesis). The main complications of neonatal and infantile impetigo are: glomerulonephritis, exfoliative dermatitis, pulmonary abscess, pulmonitis and osteomyelitis; phlyctenular, serpiginous impetigo with large and small bullae is particularly important. Treatment of neonatal and infantile dermatosis must take account of the fact that increased reabsorption and congestion are contraindications for the local application of corticoids and preparations containing salicylic and boric acid.
新生儿和儿童的皮脂腺活动最初在表皮中较为广泛,随后由于汗腺功能缺陷、循环变化、毛发增长以及易感染倾向而减少,对此需要进行有效治疗。除了遗传性“神经性皮炎类型”外,药物、食物和呼吸道过敏原以及心理因素可能在特应性皮炎的出现中起作用。发病通常在第2至6个月,面部和头皮会受到影响。临床表现因年龄而异,包括头部有结痂覆盖的脓性病灶和屈侧湿疹。家族病史、年龄和发病部位的差异将这种形式与脂溢性皮炎区分开来。臀皮炎继发于因潮湿、摩擦和浸泡以及粪便和尿液的作用(细菌生成)引起的充血。新生儿和婴儿脓疱病的主要并发症有:肾小球肾炎、剥脱性皮炎、肺脓肿、肺炎和骨髓炎;有大小水疱的泡性、匐行性脓疱病尤为重要。新生儿和婴儿皮肤病的治疗必须考虑到,增加的重吸收和充血是局部应用皮质类固醇以及含水杨酸和硼酸制剂的禁忌证。