Wittchen Hans-Ulrich, Pittrow David
Institute of Clinical Psychology and Psychotherapy and Technical University of Dresden, Dresden, Germany.
Hum Psychopharmacol. 2002 Jun;17 Suppl 1:S1-11. doi: 10.1002/hup.398.
'Depression 2000' is a major epidemiological study conducted in a representative sample of 412 primary care settings (which examined a total of 15,081 unselected patients) in Germany in order to address the current lack of information on the prevalence, recognition and treatment of depression in primary care. The study revealed that depression is a key challenge in primary care because of its prevalence (point prevalence according to ICD-10: 10.9%), type of presenting complaints and the time constraints of the doctors. Participating doctors had a very high workload (average of 62 patients per day) and perceived the management of depressed patients as a major burden. The majority of cases of depression identified met criteria for moderate or severe depression, and 51% had a chronic and/or recurrent course. A total of 55% of patients were correctly diagnosed as having a clinically significant depressive disorder, although only 21% received a diagnosis of 'definite' depression. In conclusion, these findings confirm the high prevalence of depressive disorders in primary care settings and underline the particular challenges posed by these patients. Although recognition rates among more severe major depressive patients, as well as treatments prescribed, appear to be more favourable than in previous studies, the high proportion of unrecognised patients with definite depression still raises significant concerns. It remains of continued prime importance to educate primary care doctors to better recognise depression in order to increase the patients' chances of receiving appropriate treatment.
“抑郁症2000”是一项重要的流行病学研究,该研究在德国412个初级保健机构的代表性样本中开展(共检查了15081名未经挑选的患者),旨在解决目前初级保健中关于抑郁症患病率、识别和治疗信息的匮乏问题。研究表明,抑郁症是初级保健中的一项关键挑战,原因在于其患病率(根据国际疾病分类第10版的时点患病率为10.9%)、就诊主诉类型以及医生面临的时间限制。参与研究的医生工作量极大(平均每天62名患者),并将抑郁症患者的管理视为一项重大负担。所识别出的大多数抑郁症病例符合中度或重度抑郁症标准,且51%呈慢性和/或复发性病程。共有55%的患者被正确诊断为患有具有临床意义的抑郁症,尽管只有21%被诊断为“明确的”抑郁症。总之,这些研究结果证实了初级保健机构中抑郁症的高患病率,并突显了这些患者带来的特殊挑战。尽管较严重的重度抑郁症患者的识别率以及所开具的治疗方案似乎比以往研究更为乐观,但未被识别出的明确抑郁症患者比例仍然很高,这令人深感担忧。持续对初级保健医生进行教育,使其更好地识别抑郁症,对于增加患者获得适当治疗的机会仍然至关重要。