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神经外科重症监护病房的器官捐献率

Organ donation rates in a neurosurgical intensive care unit.

作者信息

Dickerson John, Valadka Alex B, Levert Tina, Davis Kimberly, Kurian Mary, Robertson Claudia S

机构信息

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

J Neurosurg. 2002 Oct;97(4):811-4. doi: 10.3171/jns.2002.97.4.0811.

Abstract

OBJECT

The number of patients waiting for organ transplantation continues to grow, while organs are donated by very few of the thousands of potential donors who die every year. The authors' neurosurgical intensive care unit (NICU) has worked closely with coordinators from the local organ procurement organization (OPO) for many years. In this study, the authors analyze donation rates in the NICU and discuss factors that may be important in maximizing these rates.

METHODS

All referrals from the NICU to the OPO from 1996 to 1999 were analyzed. Of the 180 referrals, 98 patients were found to be medically suitable as potential donors. Another 15 patients died of hemodynamic collapse shortly after admission to the NICU. If one assumes that all 15 patients would have been suitable donors, the unsuccessful resuscitation rate becomes 15 (13.3%) of 113. Of the 98 eligible donors, consent was obtained and organs or tissue were recovered in 72, yielding a successful organ procurement rate of 73.5%.

CONCLUSIONS

Close working relationships among physicians, nurses, and OPO coordinators can result in higher donation rates than have been reported previously. Aggressive resuscitation and stabilization of all patients, early identification of potential organ donors, prompt declaration of brain death, and attempts by the OPO coordinator to build rapport with families are all important factors that may increase donation rates. Because most organ donors have sustained catastrophic intracranial events, neurosurgeons are uniquely positioned to influence organ donation policies at their hospitals and thus to salvage some benefit from tragic cases of overwhelming brain injury.

摘要

目的

等待器官移植的患者数量持续增加,而每年数千名潜在捐赠者中只有极少数进行了器官捐赠。作者所在的神经外科重症监护病房(NICU)多年来一直与当地器官获取组织(OPO)的协调员密切合作。在本研究中,作者分析了NICU的捐赠率,并讨论了可能对最大化这些比率至关重要的因素。

方法

分析了1996年至1999年从NICU转介至OPO的所有病例。在180例转介病例中,发现98例患者在医学上适合作为潜在捐赠者。另有15例患者在入住NICU后不久死于血流动力学衰竭。如果假设所有15例患者都适合作为捐赠者,那么在113例患者中复苏失败率为15例(13.3%)。在98例符合条件的捐赠者中,72例获得了同意并获取了器官或组织,成功器官获取率为73.5%。

结论

医生、护士和OPO协调员之间密切的合作关系可带来比以往报告更高的捐赠率。积极对所有患者进行复苏和稳定治疗、早期识别潜在器官捐赠者、及时宣布脑死亡以及OPO协调员努力与家属建立融洽关系都是可能提高捐赠率的重要因素。由于大多数器官捐赠者都发生了灾难性颅内事件,神经外科医生在影响其医院的器官捐赠政策方面具有独特地位,从而能从严重脑损伤的悲剧病例中挽回一些益处。

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