骨佩吉特病：临床表现、病变范围及对双膦酸盐的反应
Paget's disease of bone: presentation, extent and response to bisphosphonates.
作者信息
Wang L M, Au-Yeong M L, McKenna M J
机构信息
St. Michael's Hospital, Dún Laoghaire, Co. Dublin.
出版信息
Ir Med J. 2002 Sep;95(8):244, 246.
PMID:12405502
Abstract
According to a radiograph survey in 1982, Paget's disease of bone is common in Ireland but, to date, there have been no clinical reports. In a survey of 24 patients with Paget's disease of bone, we found monostotic disease in 8 and polyostotic disease in 16. Complications were common including deformity (21%), fracture (17%) and deafness (8%). Bisphosphonate therapy induced a remission in 22 patients.
摘要
根据1982年的一项X线片调查，爱尔兰骨Paget病很常见，但迄今为止尚无临床报告。在对24例骨Paget病患者的调查中，我们发现单骨型病变8例，多骨型病变16例。并发症很常见，包括畸形（21%）、骨折（17%）和耳聋（8%）。双膦酸盐治疗使22例患者病情缓解。
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