Pirih Flavia Q, Zablotsky Mark, Cordell Kitrina, McCauley Laurie K
University of Michigan School of Dentistry, USA.
J Mich Dent Assoc. 2009 May;91(5):38-43.
Paget's disease is the second most common bone disease following osteoporosis. Paget's disease is characterized by abnormal resorption and deposition of bone. The most widely used agents to treat Paget's disease are bisphosphonates. Bisphosphonates have been given much attention due to reports of osteonecrosis associated with their use. This case report demonstrates the placement of implants in a patient with Paget's disease on a six-month-course of bisphosphonate therapy. The patient had post-operative complications and a secondary placement but no signs of bisphosphonate-associated osteonecrosis of the jaw (ONJ). Although complications may exist, the placement of implants in a patient with Paget's disease taking bisphosphonates can have a positive outcome.
佩吉特病是仅次于骨质疏松症的第二常见骨病。佩吉特病的特征是骨的异常吸收和沉积。治疗佩吉特病最广泛使用的药物是双膦酸盐。由于有与其使用相关的骨坏死报告，双膦酸盐受到了很多关注。本病例报告展示了在一名接受双膦酸盐治疗六个月疗程的佩吉特病患者中植入种植体的情况。该患者术后出现并发症并进行了二次植入，但没有颌骨双膦酸盐相关骨坏死（ONJ）的迹象。尽管可能存在并发症，但在服用双膦酸盐的佩吉特病患者中植入种植体仍可能有积极的结果。
