Corrales Padilla H
Med Cutan Ibero Lat Am. 1975;3(1):7-21.
The histopathologic alterations of the allergic cutaneous vasculitis (fibrinoid necrosis of the walls of the small blood vessels with infiltration of neuthrophils in Karyorrexis) is seen in several entities. It is possible to divide such entities in two groups: a) Primitive allergic vasculitis in which the vascular lesion is dominant and. b) Secondary allergic vasculitis in which the vascular alterations, not constant, are integrants of variable histopathologic conditions. Many classifications have deen done on clinical and pathological bases. Such classifications are not satisfactory. A classification in base of physiopathologic and immunologic mechanisms could permit adequate therapeutic planning. In this paper we consider the secondary vasculitis only. The secondary angitis are seen in: 1) Difuse colagen diseases. 3) Conditions related to infections or inflamatory processes. 3) Angitis produced by drugs. 4) Conditions produced by insects or parasites bites. 5) Heterogeneous group that include diferent tipes of not necrotizing sistemic angitis in uhich, some times, trombosant and necrotizing processes are associated.
变应性皮肤血管炎的组织病理学改变（小血管壁纤维蛋白样坏死伴核碎裂的中性粒细胞浸润）可见于多种疾病。这些疾病可分为两组：a）原发性变应性血管炎，其中血管病变占主导；b）继发性变应性血管炎，其中血管改变不恒定，是多种组织病理学情况的组成部分。已经基于临床和病理进行了许多分类。这些分类并不令人满意。基于生理病理和免疫机制的分类可以允许进行适当的治疗规划。在本文中，我们仅考虑继发性血管炎。继发性血管炎见于：1）弥漫性胶原病。3）与感染或炎症过程相关的情况。3）药物引起的血管炎。4）昆虫或寄生虫叮咬引起的情况。5）异质性组，包括不同类型的非坏死性系统性血管炎，有时伴有血栓形成和坏死过程。
