Rodriguez G, Rueda L A
Med Cutan Ibero Lat Am. 1975;3(2):111-8.
The first Latin-American case of a relapsing digital fibromatosis in a 6 months old child is presented by the authors. With the H.E. staining cytoplasmatic inclusions were found in the fibroblasts. For the first time the presence of cellular synctitiums in the entity is described. Many of these synctitiums contain inclusion bodies. This inclusion observed with electron microscope was constituted by a considerable amount of filaments condensing in the center and the well developed stages occupying most of the cyloplasm. No viral particles were found. The accumulation of filaments in the fibroblast causes a degenerative final stage of the cells. The possibility whether this inclusion represents an accumulation of the synthetised fibers by the fibroblast or a conglomerate is not determined by this study. An extensive review of the literature on this subject is made by the authors.
作者报告了拉丁美洲首例6个月大儿童复发性指纤维瘤病病例。苏木精-伊红染色显示成纤维细胞中有细胞质包涵体。首次描述了该病变中细胞合体的存在。许多这些合体含有包涵体。电子显微镜观察到的这种包涵体由大量细丝在中心聚集而成,发育良好的阶段占据大部分细胞质。未发现病毒颗粒。成纤维细胞中细丝的积累导致细胞的退行性终末期。本研究未确定这种包涵体是代表成纤维细胞合成纤维的积累还是聚集体。作者对该主题的文献进行了广泛综述。