Jun Stephanie, Stollman Neil
Department of Internal Medicine, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA.
Best Pract Res Clin Gastroenterol. 2002 Aug;16(4):529-42. doi: 10.1053/bega.2002.0328.
Diverticulosis, which is an acquired condition marked by mucosal herniation through defects in the colonic wall, has been termed both a "disease of the 20th century" and a "disease of Western civilization" due to its increasing prevalence in modern times and its striking geographical variability. Both of these epidemiological observations may provide interesting insights into the pathophysiology of diverticulosis. This chapter will review the known epidemiology of diverticulosis coli and its main complications: diverticulitis and diverticular haemorrhage. Where possible, attempts will be made to place these observational reports in the context of both the cause and clinical behaviour of this disorder.
憩室病是一种后天性疾病，其特征为黏膜通过结肠壁的缺损处疝出，由于其在现代的患病率不断上升以及显著的地域差异，它被称为“20世纪的疾病”和“西方文明病”。这两种流行病学观察结果可能为憩室病的病理生理学提供有趣的见解。本章将回顾结肠憩室病的已知流行病学及其主要并发症：憩室炎和憩室出血。在可能的情况下，将尝试把这些观察报告置于该疾病的病因和临床行为的背景下。
