Sawai J, Doi R, Maekawa Y, Yoshikawa T, Kojima H
Department of Applied Chemistry, Kanagawa Institute of Technology, 1030 Shimo-Ogino, Atsugi, Kanagawa 243-0292, Japan.
J Ind Microbiol Biotechnol. 2002 Nov;29(5):296-8. doi: 10.1038/sj.jim.7000314.
The applicability of indirect conductimetric assays for evaluation of antibacterial activity was examined. The minimal inhibitory concentration (MIC) obtained by the indirect method was consistent with that by the direct conductimetric assay and the turbidity method. The indirect assay allows use of growth media, which cannot be used in the direct conductimetric assay, making it possible to evaluate the antibacterial activity of insoluble or slightly soluble materials with high turbidity, such as antibacterial ceramic powders.
研究了间接电导测定法在评估抗菌活性方面的适用性。通过间接法获得的最低抑菌浓度(MIC)与直接电导测定法和比浊法获得的结果一致。间接测定法允许使用直接电导测定法中无法使用的生长培养基,从而能够评估不溶性或微溶性且具有高浊度的材料(如抗菌陶瓷粉末)的抗菌活性。