Tabak Lawrence A
National Institute of Dental and Craniofacial Research, NIH, 31 Center Drive MSC 2290, Bethesda, MD 20892-2290, USA.
J Am Coll Dent. 2002 Summer;69(3):27-31.
Popular attention has focused on connections between single nucleotide polymorphisms (SNPs) where single genome irregularities are associated with biological deficiencies. The more significant and more difficult work will come through seeking to understand the proteonomics--the way sets of genes are expressed as proteins, and ultimately in larger and more complex entities. Future developments will take place at the interfaces among various disciplines. We are already seeing the introduction of diagnostic tests based on the new genomics in dental offices. New skills will be needed to bring these emerging developments into practice.
公众的注意力集中在单核苷酸多态性（SNP）之间的联系上，即单个基因组异常与生物学缺陷相关联。更重要且更具挑战性的工作将是致力于理解蛋白质组学——基因如何表达为蛋白质，以及最终在更大、更复杂的实体中的表达方式。未来的发展将在各学科的交叉领域发生。我们已经看到牙科诊所引入了基于新基因组学的诊断测试。要将这些新出现的进展付诸实践，将需要新的技能。
