Vaisse V, Matard B, Assouly P, Jouannique C, Reygagne P
Unité de Dermatologie, Hôpital Tenon, 4, rue de la Chine, 75020 Paris.
Ann Dermatol Venereol. 2003 Jun-Jul;130(6-7):607-10.
Postmenopausal frontal fibrosing alopecia is a scarring alopecia that has been recently described by Kossard in 1994 and rarely reported in the literature.
We have conducted a retrospective clinical and histological study of a series of 20 cases of postmenopausal frontal fibrosing alopecia. The results, in agreement with those in the literature, revealed the stereotyped nature of this entity.
All the clinical and histological data suggest that postmenopausal frontal fibrosing alopecia is a clinical form of lichen planopilaris occurring in elderly women. As with lichen planopilaris its physiopathology is unknown. However, in analogy with other lichen-like dermatoses, a lymphocyte T-mediated autoimmune reaction appears to play a predominant part in its genesis.
绝经后额部纤维性脱发是一种瘢痕性脱发，1994年由科索德首次描述，在文献中鲜有报道。
我们对20例绝经后额部纤维性脱发患者进行了回顾性临床和组织学研究。结果与文献报道一致，揭示了该疾病的典型特征。
所有临床和组织学数据表明，绝经后额部纤维性脱发是老年女性发生的扁平苔藓样毛发扁平苔藓的一种临床形式。与扁平苔藓样毛发扁平苔藓一样，其发病机制尚不清楚。然而，与其他苔藓样皮肤病类似，T淋巴细胞介导的自身免疫反应似乎在其发病过程中起主要作用。
