Sebastiani Laura, Ghelarducci Brunello
Dipartimento di Fisiologia e Biochimica, Università di Pisa, via S. Zeno 31, 56127 Pisa, Italy.
Exp Brain Res. 2002 Nov;147(2):264-7. doi: 10.1007/s00221-002-1269-4. Epub 2002 Oct 3.
The effects of medial prefrontal cortex early lesion (mPFl) on classical conditioned bradycardia (CB) were studied in adult rabbits. In lesioned rabbits, baseline HR, orienting and conditioned HR responses were similar to controls. Since mPFl alone does not affect CB, while it is known to prevent the HR increments produced by a concomitant early cerebellar vermal ablation, medial prefrontal cortex must be involved in the reorganization of the CB control mechanisms following early cerebellar vermal ablation.
在成年兔中研究了内侧前额叶皮质早期损伤（mPFl）对经典条件性心动过缓（CB）的影响。在损伤的兔子中，基线心率、定向和条件性心率反应与对照组相似。由于单独的mPFl并不影响CB，而已知它能阻止伴随早期小脑蚓部切除所产生的心率增加，因此内侧前额叶皮质必定参与了早期小脑蚓部切除后CB控制机制的重组。
