Shah Sanjiv S, McGowan Joseph P, Smith Cheryl, Blum Steve, Klein Robert S
Division of Infectious Diseases, Bronx-Lebanon Hospital Center, Bronx, NY, USA.
Clin Infect Dis. 2002 Nov 15;35(10):1238-43. doi: 10.1086/343048. Epub 2002 Oct 21.
We retrospectively examined comorbid conditions and health maintenance in 198 patients aged > or =55 years who attended 3 New York City human immunodeficiency virus (HIV) clinics between 1 January 1990 and 30 June 1998. Annual influenza and pneumococcal vaccinations within 5 years were given in 82% and 86% of patients, respectively. Among 57 women, 79% had a Papanicolaou smear within 1 year, and 53% had a mammogram within 2 years. Of 165 patients who received care after 1 July 1996, 147 (89%) had comorbid conditions (mean number of conditions, 2.4), and 133 (81%) received HIV-unrelated medications (mean number of medications, 2.7). Receipt of highly active antiretroviral therapy, its discontinuation because of toxicity, and having an undetectable HIV load were not related to comorbid conditions or use of concurrent medications. Comorbid conditions and use of concurrent HIV-unrelated medications need not adversely affect treatment of HIV-infected older individuals, but increased attention to health maintenance may be necessary.
我们回顾性研究了198例年龄≥55岁的患者的合并症及健康维护情况，这些患者于1990年1月1日至1998年6月30日期间在纽约市的3家人类免疫缺陷病毒（HIV）诊所就诊。分别有82%和86%的患者在5年内接种了年度流感疫苗和肺炎球菌疫苗。在57名女性患者中，79%在1年内进行了巴氏涂片检查，53%在2年内进行了乳房X光检查。在1996年7月1日后接受治疗的165例患者中，147例（89%）有合并症（平均合并症数量为2.4种），133例（81%）接受了与HIV无关的药物治疗（平均药物数量为2.7种）。接受高效抗逆转录病毒治疗、因毒性而停药以及HIV病毒载量检测不到与合并症或同时使用药物无关。合并症和同时使用与HIV无关的药物不一定会对感染HIV的老年患者的治疗产生不利影响，但可能需要更加关注健康维护。
