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采用莫氏显微外科手术治疗婴儿指(趾)纤维瘤。

Infantile digital fibroma treated with mohs micrographic surgery.

作者信息

Albertini John G, Welsch Michael Jude, Conger Leo A, Libow Lester F, Elston Dirk M

机构信息

Brooke Army Medical Center, Fort Sam Houston, TX, USA.

出版信息

Dermatol Surg. 2002 Oct;28(10):959-61. doi: 10.1046/j.1524-4725.2002.02072.x.

Abstract

BACKGROUND

Infantile digital fibroma (IDF) is a rare benign fibrous tumor of childhood that frequently recurs despite local excision. Conservative, nonsurgical management may result in regression and/or joint deformity.

OBJECTIVE

To describe the histologic features of IDF and discuss a case excised using Mohs micrographic surgery (MMS).

METHODS

Case report and review of the clinical, histologic, and ultrastructural features.

RESULTS

Characteristic inclusion bodies of actin were identified with hematoxylin and eosin, Masson's trichrome, and rapid actin immunostain. The tumor was debulked and the majority was removed after one stage of MMS, except where the deep margin approached the joint space. The defect healed by secondary intention. At 2 years the patient had no recurrence or functional joint deformity.

CONCLUSION

MMS is a surgical treatment option for IDF.

摘要

背景

婴儿指纤维瘤(IDF)是一种罕见的儿童期良性纤维瘤,尽管进行了局部切除,但仍经常复发。保守的非手术治疗可能导致肿瘤消退和/或关节畸形。

目的

描述婴儿指纤维瘤的组织学特征,并讨论一例采用莫氏显微外科手术(MMS)切除的病例。

方法

病例报告以及对临床、组织学和超微结构特征的回顾。

结果

通过苏木精-伊红染色、马松三色染色和快速肌动蛋白免疫染色鉴定出特征性的肌动蛋白包涵体。肿瘤大部分经MMS一期手术切除减容,除深部切缘接近关节间隙处。缺损通过二期愈合。2年后,患者无复发且关节无功能畸形。

结论

MMS是婴儿指纤维瘤的一种手术治疗选择。

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