Failla Valérie, Wauters Odile, Nikkels-Tassoudji Nazli, Carlier Alain, André Josette, Nikkels Arjen F
Departments of Dermatology and.
Rare Tumors. 2009 Dec 28;1(2):e47. doi: 10.4081/rt.2009.e47.
Infantile digital fibromatosis (IDF) is a rare benign fibroproliferative tumor of early childhood. IDF preferentially affects the fingers and the toes. Malignant transformation or metastases have never been reported. Surgical treatment has been advocated previously but local recurrences were observed frequently. Recent literature supports clinical surveillance without any medical or surgical intervention as spontaneous regression usually occurs after two to three years. A six-month-old Caucasian girl with IDF on the left fourth digit is presented here. The tumor progressively increased in size after birth. Topical imiquimod cream and diflucortolone valerate cream, both displaying antifibrotic properties, had no effect on tumor growth. Currently the lesion size remains stable without any treatment. Early recognition of IDF is important in order to avoid unnecessary surgical intervention that may prove to be potentially aggravating, unless serious functional or cosmetic concerns intervene. Parents should be reassured concerning the benign nature of IDF and be informed that spontaneous involution of IDF might be expected.
婴儿指纤维瘤病（IDF）是一种儿童早期罕见的良性纤维增生性肿瘤。IDF 优先累及手指和脚趾。从未有过恶性转化或转移的报道。此前一直提倡手术治疗，但局部复发经常出现。最近的文献支持临床观察，无需任何药物或手术干预，因为通常在两到三年后会出现自发消退。本文介绍了一名 6 个月大的患有左侧第四指 IDF 的白种女孩。肿瘤在出生后逐渐增大。具有抗纤维化特性的局部咪喹莫特乳膏和戊酸倍他米松乳膏对肿瘤生长均无作用。目前，在未进行任何治疗的情况下，病变大小保持稳定。早期识别 IDF 很重要，以避免可能被证明具有潜在加重作用的不必要手术干预，除非存在严重的功能或美容问题。应让家长放心 IDF 的良性性质，并告知他们 IDF 可能会自发消退。
