Driban N E, Bertranou E G
Med Cutan Ibero Lat Am. 1975;3(3):213-22.
Two cases of Progeria of the adult (Werner's Syndrome) are presented. The outstanding characteristic of the mentioned syndrome is an early, progressive and fatal aging of the patient. The study of those two cases suggested, first: a literature search which has shown 140 references to the Werner's Syndrome up to 1971, and second: a clinical features review about general manifestations and specific particularities concerning the skin, cardiovascular system, eyes, glandular system, laboratory tests, etc. Our two patients, who respond to the signs required by Thannhauser for the diagnosis of the Werner's Syndrome, were very useful to clarify the clinical features review undestalren.
本文报告了两例成人早老症(沃纳综合征)。上述综合征的突出特征是患者出现过早、进行性且致命的衰老。对这两例病例的研究表明,其一:通过文献检索发现,截至1971年已有140篇关于沃纳综合征的参考文献;其二:对临床特征进行了回顾,内容涉及一般表现以及皮肤、心血管系统、眼睛、腺体系统、实验室检查等方面的具体特点。我们的两名患者符合坦豪泽诊断沃纳综合征所需的体征,这对于明确所理解的临床特征非常有帮助。