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中国广西1至6岁儿童脑瘫患病率

Prevalence of cerebral palsy in children aged 1 - 6 in Guangxi, China.

作者信息

Liang Youling, Guo Xianming, Yang Guanglin, Yan Xiumei, Li Xiaoli, Li Guangyong, Lan Dongping, Li Shuxian, Wang Yong, Ding Haoping, Liu Yanling, Liu Jianmeng, Li Song, Lin Qing

机构信息

The Child and Maternity Hospital of Guangxi Zhuang Autonomous Region, Nanning 530003, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2002 May;36(3):164-6.

PMID:12410948
Abstract

OBJECTIVE

To study the prevalence of cerebral palsy (here in after referred to CP) in children aged 1 - 6 in Guangxi, China, and its epidemiologic characteristics and relevant risk factors.

METHODS

Investigations on the prevalence and etiology of CP in children at ages of 1 - 6 were conducted in Nanning, Hengxian and Qinzhou of Guangxi from June to December in 1998, with a cluster sampling.

RESULTS

Totally, 150 806 children aged 1 - 6 were investigated in Nanning, Hengxian and Qinzhou of Guangxi, with 89 418 boys and 61 388 girls. Among them, 193 children were diagnosed as CP, with a prevalence rate of 1.28 per thousand, higher in boys (136 cases, 1.52 per thousand ) than in girls (57 cases, 0.93 per thousand ), with statistical significance (chi(2) = 9.536 7, P = 0.02). Logistic regression analysis showed that risk factors for CP were children who could not cry after birth (neonatal asphyxia), Apgar score less than eight, delivery at lower level of maternity hospital, number of mother's gravidity, no prenatal checks for mothers, and taking antipyretics and preserved food with salt during pregnancy.

CONCLUSIONS

Prevalence of CP in children of Guangxi was at a lower level in comparison with that in other areas at home and abroad, which, maybe, was related with the lower neonatal survival and higher infant mortality.

摘要

目的

研究中国广西1 - 6岁儿童脑性瘫痪(以下简称脑瘫)的患病率、流行病学特征及相关危险因素。

方法

1998年6月至12月,采用整群抽样的方法,对广西南宁、横县和钦州1 - 6岁儿童脑瘫的患病率及病因进行调查。

结果

广西南宁、横县和钦州共调查1 - 6岁儿童150806名,其中男89418名,女61388名。共诊断出脑瘫患儿193例,患病率为千分之1.28,男性患病率(136例,千分之1.52)高于女性(57例,千分之0.93),差异有统计学意义(χ² = 9.536 7,P = 0.02)。Logistic回归分析显示,脑瘫的危险因素包括出生后不哭(新生儿窒息)、阿氏评分低于8分、在基层产院分娩、母亲妊娠次数、母亲未进行产前检查以及孕期服用退烧药和腌制食品。

结论

广西儿童脑瘫患病率低于国内外其他地区,这可能与新生儿存活率较低和婴儿死亡率较高有关。

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